Translation for this volume by Lydia Patton of Chapter 9 (pages 179-200) of Émilie du Châtelet's Institutions de Physique (Foundations of Physics). Original publication date 1750. Paris: Chez Prault Fils.

Between 2013 and 2016, West Africa experienced the largest ever outbreak of Ebola Virus Disease. In the absence of registered treatments or vaccines to control this lethal disease, the World Health Organization coordinated and supported research to expedite identification of interventions that could control the outbreak and improve future control efforts. Consequently, the World Health Organization Research Ethics Review Committee was heavily involved in reviews and ethics discussions. It reviewed 24 new and 22 amended protocols for research studies including interventional (...) and observational studies. WHO-ERC provided the reviews within on average 6 working days. The WHO-ERC often could not provide immediate approval of protocols for reasons which were not Ebola Virus Disease specific but related to protocol inconsistencies, missing information and complex informed consents. WHO-ERC considerations on Ebola Virus Disease specific issues are presented. To accelerate study approval in future public health emergencies, we recommend: internally consistent and complete submissions with information documents in language participants are likely to understand, close collaboration between local and international researchers from research inception, generation of template agreements for data and sample sharing and use during the ongoing global consultations on bio-banks, formation of Joint Scientific Advisory and Data Safety Review Committees for all studies linked to a particular intervention or group of interventions, formation of a Joint Ethics Review Committee with representatives of the Ethics Committees of all institutions and countries involved to strengthen reviews through the different perspectives provided without the ‘opportunity costs’ for time to final approval of multiple, independent reviews, direct information exchange between the chairs of advisory, safety review and ethics committees, more Ethics Committee support for investigators than is standard and a global consultation on criteria for inclusion of pregnant women and children in interventional studies for conditions which put them at particularly high risk of mortality or other irreversible adverse outcomes under standard-of-care. (shrink)

Background Between 2013 and 2016, West Africa experienced the largest ever outbreak of Ebola Virus Disease. In the absence of registered treatments or vaccines to control this lethal disease, the World Health Organization coordinated and supported research to expedite identification of interventions that could control the outbreak and improve future control efforts. Consequently, the World Health Organization Research Ethics Review Committee was heavily involved in reviews and ethics discussions. It reviewed 24 new and 22 amended protocols for research studies including (...) interventional and observational studies. WHO-ERC reviews WHO-ERC provided the reviews within on average 6 working days. The WHO-ERC often could not provide immediate approval of protocols for reasons which were not Ebola Virus Disease specific but related to protocol inconsistencies, missing information and complex informed consents. WHO-ERC considerations on Ebola Virus Disease specific issues are presented. Conclusions To accelerate study approval in future public health emergencies, we recommend: internally consistent and complete submissions with information documents in language participants are likely to understand, close collaboration between local and international researchers from research inception, generation of template agreements for data and sample sharing and use during the ongoing global consultations on bio-banks, formation of Joint Scientific Advisory and Data Safety Review Committees for all studies linked to a particular intervention or group of interventions, formation of a Joint Ethics Review Committee with representatives of the Ethics Committees of all institutions and countries involved to strengthen reviews through the different perspectives provided without the ‘opportunity costs’ for time to final approval of multiple, independent reviews, direct information exchange between the chairs of advisory, safety review and ethics committees, more Ethics Committee support for investigators than is standard and a global consultation on criteria for inclusion of pregnant women and children in interventional studies for conditions which put them at particularly high risk of mortality or other irreversible adverse outcomes under standard-of-care. (shrink)

Strategies based on performance measurement and feedback are commonly used to support quality improvement among nurses. These strategies require practice change, which, for nurses, rely to a large extent on their capacity to coordinate with each other effectively. However, the levers for coordinated action are difficult to mobilize. This discussion paper offers a theoretical reflection on the challenges related to coordinating nurses' actions in the context of practice changes initiated by performance measurement and feedback strategies. We explore how Jürgen Habermas' (...) theory of Communicative Action may shed light on the issues underlying nurses' collective actions and self‐determination in practice change and the implications for the design of strategies based on performance measurement and feedback. Based on this theory, we propose differences between communicative and functional coordination according to the nature of the actions and the purposes involved. The domains of action underlying these coordination processes, which Habermas referred to as the lifeworld and the system, are then used to draw a parallel with aspects of nursing practice. Further exploration of these concepts allows us to consider the tensions between the demands of the system and the self‐determination of nurses within their practice. (shrink)

This study examines the relationships of servant leadership to organizational commitment, voice behaviors, and antisocial behaviors. Adopting a multifaceted approach to commitment, we hypothesized that servant leadership would be positively related to affective, normative, and perceived sacrifice commitment, but unrelated to few alternatives commitment. We further hypothesized that affective commitment would be positively related to voice behaviors, controlling for the other commitment components, and would mediate a positive relationship between servant leadership and voice behaviors. Similarly, we hypothesized that normative commitment (...) would be negatively related to antisocial behaviors, controlling for the other commitment components, and would mediate a negative relationship between servant leadership and antisocial behaviors. These predictions were tested using matched data from a sample of 181 Canadian customer service employees and their managers. Results largely supported the above predictions. Importantly, affective commitment mediated a positive relationship between servant leadership and voice behaviors. Yet, while servant leadership was positively related to normative commitment and the latter was negatively related to antisocial behaviors, the indirect effect of servant leadership on these behaviors through normative commitment was nonsignificant. Theoretical implications and future research directions are discussed. (shrink)

Après avoir présenté l’institution récente de la kafâla, qui fut légalisée en Algérie en 1984 et au Maroc en 1993 en faveur des enfants abandonnés et en substitution au modèle prohibé de l’adoption, l’article propose une analyse des données recueillies lors d’une enquête ethnographique menée de 2005 à 2009. Elle révèle que l’enfant illégitime encourt davantage le risque d’être abandonné à la naissance s’il est de sexe masculin. En revanche, s’il est de sexe féminin, il bénéficie de plus de chances (...) de faire l’objet d’un don provisoire, direct et négocié, et surtout d’être adopté ou recueilli en kafâla suite à son abandon en institution. (shrink)

Après avoir présenté l’institution récente de la kafâla, qui fut légalisée en Algérie en 1984 et au Maroc en 1993 en faveur des enfants abandonnés et en substitution au modèle prohibé de l’adoption, l’article propose une analyse des données recueillies lors d’une enquête ethnographique menée de 2005 à 2009. Elle révèle que l’enfant illégitime encourt davantage le risque d’être abandonné à la naissance s’il est de sexe masculin. En revanche, s’il est de sexe féminin, il bénéficie de plus de chances (...) de faire l’objet d’un don provisoire, direct et négocié, et surtout d’être adopté ou recueilli en kafâla suite à son abandon en institution. (shrink)

Un colloque international et pluridisciplinaire a rassemblé les 4, 5 et 6 octobre 2006 au Collège de France des anthropologues, juristes, historiens et philosophes spécialistes des questions de parenté. La rencontre, inscrite dans la continuité d’un précédent colloque consacré à l’alliance, portait cette fois sur « L’argument de la filiation, aux fondements des sociétés européennes et méditerranéennes anciennes et actuelles ». L’objectif premier des organisateurs était de construire un objet...

Dans son ouvrage La libération animale, Peter Singer développe trois grandes idées : le principe d'égale considération des intérêts, le rejet du spécisme et la nécessité de mettre un terme à certains types d'exploitation des animaux, notamment ceux qui ont trait à la recherche et à l'élevage industriel. Cette oeuvre phare a connu un retentissement immense, à tel point que sa publication, en 1975, a été présentée comme le moment clef dans l'émergence du mouvement éponyme. Cependant, le mouvement de libération (...) animale ne saurait se réduire à la seule pensée singerienne. Ce mouvement extrêmement protéiforme a fait l'objet de débats intenses à l'interne, entre les défenseurs des animaux eux-mêmes qui privilégient des approches diverses, comme à l'externe, entre ceux qui défendent le statu quo ou contestent les arguments animalistes. L'objet de ce recueil est de revenir sur le lien entre le mouvement de libération animale et les théories de Peter Singer qui, à tort ou à raison, en est perçu comme le père fondateur. Comment l'éthique animale de l'auteur a-t-elle été accueillie depuis la publication de La libération animale, et comment a-t-elle évolué? Quelle place la doctrine utilitariste occupe-t-elle dans le travail de Singer et dans les débats qu'il a engendrés? C'est en effet dans cette doctrine parente que résident les écueils auxquels s'est heurté le travail de l'auteur. C'est aussi là que son système a trouvé sa force et sa simplicité caractéristiques. C'est aussi, semble-t-il, ce qui fait la fécondité de ses idées. (shrink)

Arguments for the effectiveness, and even the indispensability, of mathematics in scientific explanation rely on the claim that mathematics is an effective or even a necessary component in successful scientific predictions and explanations. Well-known accounts of successful mathematical explanation in physical science appeals to scientists’ ability to solve equations directly in key domains. But there are spectacular physical theories, including general relativity and fluid dynamics, in which the equations of the theory cannot be solved directly in target domains, and yet (...) scientists and mathematicians do effective work there (McLarty 2023, Elder 2023). Building on extant accounts of structural scientific explanation (Bokulich 2011, Leng 2021), I argue that philosophical accounts of the role of equations in scientific explanation need not rely on scientists’ ability to solve equations independently of their understanding of the empirical or experimental context. For instance, the process of formulating solutions to equations can involve significant appeal to information about experimental contexts (Curiel 2010) or of physically similar systems (Sterrett 2023). Working from a close analysis of work in fluid mechanics by Martin Bazant and Keith Moffatt (2005), I propose an account of heuristic structural explanation in mathematics (Einstein 1921, Pincock 2021), which explains how physical explanations can be constructed even in domains where basic equations cannot be solved directly. (shrink)

Although beef and dairy production in Alberta, Canada, enjoys strong public support, there are enduring public concerns, including farm animal welfare. Evolving codes of practice and animal care councils prescribe changes and improvements to many areas of farm management, and may be seen by farmers as an appropriate response to public animal welfare concerns. However, codes of practice do not address every animal welfare concern, and new concerns can arise over time. Drawing on social practice theory and in-depth field research (...) with 36 cattle and dairy farmers, this paper explores the materials, competencies, and meanings of four animal husbandry practices: branding, dehorning, weaning, and on-farm handling and moving. Findings show that branding and dehorning are evolving slowly with attention to pain management, but remain firmly rooted in ranching tradition and communities of practice. Weaning and animal handling practices are evolving more quickly with attention to changing materials, attitudes, and values that are more prevalent within producer communities. (shrink)

The Marburg neo-Kantians argue that Hermann von Helmholtz's empiricist account of the a priori does not account for certain knowledge, since it is based on a psychological phenomenon, trust in the regularities of nature. They argue that Helmholtz's account raises the 'problem of validity' (Gueltigkeitsproblem): how to establish a warranted claim that observed regularities are based on actual relations. I reconstruct Heinrich Hertz's and Ludwig Wittgenstein's Bild theoretic answer to the problem of validity: that scientists and philosophers can depict the (...) necessary a priori constraints on states of affairs in a given system, and can establish whether these relations are actual relations in nature. The analysis of necessity within a system is a lasting contribution of the Bild theory. However, Hertz and Wittgenstein argue that the logical and mathematical sentences of a Bild are rules, tools for constructing relations, and the rules themselves are meaningless outside the theory. Carnap revises the argument for validity by attempting to give semantic rules for translation between frameworks. Russell and Quine object that pragmatics better accounts for the role of a priori reasoning in translating between frameworks. The conclusion of the tale, then, is a partial vindication of Helmholtz's original account. (shrink)

This paper will focus on a famous nineteenth century debate over the physiology of perception between Ewald Hering and Hermann von Helmholtz. This debate is often explained as a contest between empiricism (Helmholtz) and nativism (Hering) about perception. I will argue that this is only part of the picture. Hering was a pioneer of Lamarckian explanations, arguing for an early version of the biogenetic law. Hering explains physical processes, including perception, in terms of ‘organic memory’ that is supported by ‘vital (...) forces’ located throughout the body. Helmholtz, on the other hand, argues that vital forces are in direct conflict with the results he and others proved in the 1840s and 50s on the conservation of force. The battleground of the debate was the interpretation of Johannes Müller’s ‘law of specific nerve energies’, which Hering interpreted in terms of vital forces, and Helmholtz interpreted using a naturalized neo-Kantian approach. In the end, the debate revealed deep fissures in nineteenth century accounts of scientific explanation, as well as in the conception of how physiology, psychology, physics, and philosophy are related. (shrink)

There are an increasing number of cell therapy approaches being studied and employed world‐wide. An emerging area in this field is the use of human pluripotent stem cell (hPSC) products for the treatment of injuries/diseases that cannot be effectively managed through current approaches. However, as with any cell therapy, vast numbers of functional and safe cells are required. Bioreactors provide an attractive avenue to generate clinically relevant cell numbers with decreased labour and decreased batch to batch variation. Yet, current methods (...) of performing quality control are not readily scalable to the cell densities produced during bioreactor scale‐up. One potential solution is the application of inducible/controllable suicide genes that can trigger cell death in unwanted cell types. These types of approaches have been demonstrated to increase the quality and safety of the resultant cell products. In this review, we will provide background on these approaches and how they could be used together with bioreactor technology to create effective bioprocesses for the generation of high quality and safe hPSCs for use in regenerative medicine approaches. (shrink)

Si les animaux d’élevage comme les animaux d’expérimentation intéressent depuis une trentaine d’années de plus en plus de personnes – de chercheurs, de militants –, les animaux dit de compagnie, en revanche, semblent toujours pâtir du préjugé selon lequel, parce qu’ils relèveraient d’une relation privée, ils seraient sans intérêt scientifique ou philosophique. Donna Haraway propose une façon tout à fait singulière de court-circuiter cet arrêt de la pensée afin de pouvoir re-problématiser cette relation à nouveau frais. Ce qui change immédiatement, (...) c’est le caractère non plus privé mais politique de cette co-relation : l’histoire biologique et politique qui nous unit à ces animaux dit de compagnie apparus massivement dans les années 1970 est toute aussi complexe que celle que nous partageons par ailleurs avec nos autres espèces compagnes. Comment raconter cette histoire et hériter des conséquences de cette co-évolution? Comment prendre au sérieux, moralement, politiquement nos relations inter-espèces? (shrink)

In my dissertation, I present Hermann Cohen's foundation for the history and philosophy of science. My investigation begins with Cohen's formulation of a neo-Kantian epistemology. I analyze Cohen's early work, especially his contributions to 19th century debates about the theory of knowledge. I conclude by examining Cohen's mature theory of science in two works, The Principle of the Infinitesimal Method and its History of 1883, and Cohen's extensive 1914 Introduction to Friedrich Lange's History of Materialism. In the former, Cohen gives (...) an historical and philosophical analysis of the foundations of the infinitesimal method in mathematics. In the latter, Cohen presents a detailed account of Heinrich Hertz's Principles of Mechanics of 1894. Hertz considers a series of possible foundations for mechanics, in the interest of finding a secure conceptual basis for mechanical theories. Cohen argues that Hertz's analysis can be completed, and his goal achieved, by means of a philosophical examination of the role of mathematical principles and fundamental concepts in scientific theories. (shrink)

This essay will first present a vignette of Luxemburg’s life and work, referring to classic and recent biographies. Following that, section 3 examines concepts of the state and nation in Hegel, Marx, Engels, and Lenin. The subject of section 4 is Luxemburg’s substantial work of political economy, The Accumulation of Capital. It is a most significant achievement, analyzing the contradictions of the capitalist state and its role in driving imperialist expansion and colonialism. Section 5 traces how Luxemburg’s political economy in (...) Accumulation underwrites her interventions in the heated debates over Polish independence. And section 6 concludes with remarks on Luxemburg’s significance for philosophy and political thought. (shrink)

Kant's account of space as an infinite given magnitude in the Critique of Pure Reason is paradoxical, since infinite magnitudes go beyond the limits of possible experience. Michael Friedman's and Charles Parsons's accounts make sense of geometrical construction, but I argue that they do not resolve the paradox. I argue that metaphysical space is based on the ability of the subject to generate distinctly oriented spatial magnitudes of invariant scalar quantity through translation or rotation. The set of determinately oriented, constructed (...) geometrical spaces is a proper subset of metaphysical space, thus, metaphysical space is infinite. Kant's paradoxical doctrine of metaphysical space is necessary to reconcile his empiricism with his transcendental idealism. (shrink)

In the early 1900s, Russell began to recognize that he, and many other mathematicians, had been using assertions like the Axiom of Choice implicitly, and without explicitly proving them. In working with the Axioms of Choice, Infinity, and Reducibility, and his and Whitehead’s Multiplicative Axiom, Russell came to take the position that some axioms are necessary to recovering certain results of mathematics, but may not be proven to be true absolutely. The essay traces historical roots of, and motivations for, Russell’s (...) method of analysis, which are intended to shed light on his view about the status of mathematical axioms. I describe the position Russell develops in consequence as “immanent logicism,” in contrast to what Irving (1989) describes as “epistemic logicism.” Immanent logicism allows Russell to avoid the logocentric predicament, and to propose a method for discovering structural relationships of dependence within mathematical theories. (shrink)

I examine the role of inference from experiment in theory building. What are the options open to the scientific community when faced with an experimental result that appears to be in conflict with accepted theory? I distinguish, in Laudan's (1977), Nickels's (1981), and Franklin's (1993) sense, between the context of pursuit and the context of justification of a scientific theory. Making this distinction allows for a productive middle position between epistemic realism and constructivism. The decision to pursue a new or (...) a revised theory in response to the new evidence may not be fully rationally determined. Nonetheless, it is possible to distinguish the question of whether there is reason to pursue a theory from the question of whether that theory, once it has been pursued over time, solves a problem of interest to science. I argue that, in this context, there is a solid way to distinguish between the contexts of pursuit and of justification, on the basis of a theory's evidential support and problem-solving ability. (shrink)

Chora – le «cratère à mélanger» maternel, vannant et secouant de Platon – remplit «l’écart explicatif» entre les paradigmes formels «intelligibles et toujours existants» (48E5) et un monde encosmique «généré et visible». Proclus traite la gamme polysémique des termes utilisés par Platon pour chôra : hypodochê (réceptacle), kratêr (cratère à mélanger), etc., comme désignant des forces actives dans un univers où la sympathie cosmique règne, à partir des plus élevées, jusqu’aux plus basses manifestations de l’ «Un» transcendant. L’univers proclusien est (...) un «hénothéisme», dans lequel une «unité» dominante surgit sur la totalité de l’Être et du Devenir. Chôra permet à la fois au monde immatériel et au monde matériel de recevoir, de manière appropriée à chacun, les mêmes dons transcendants que leurs homologues intellectifs‑intelligibles superieurs. Aucun niveau de la réalité n’est dépourvu de cette donation. La réceptivité (hypodochê), indéterminée, mais toujours active, est présente à tous les niveaux. L’âme reçoit l’Intellect, la temporalité reçoit le temps monadique, la matière reçoit la structure géométrique polyédrique, etc. Chôra n’est pas l’equivalent de la matière, mais permet à la matière d’être imprimée par des paradigmes formels. Dans son rôle de «cratère à mélanger», elle protège la matière de sa potentielle itérabilité et dissolution infinie. Dans l’univers proclusien, le Bien atteint la dernière et la plus extrême de ses limites, il est espace et lieu, recevant à la fois l’expansivité et une capacité à donner place à la forme pour qu’elle puisse s’imposer à la matière. Après tout, les dons lui sont accordés depuis la plus haute hypostase, celle de la Limite et de l’Illimité, premier niveau après l’Un lui‑même. Vitale pour la création, la Chôra est alors la «mère» de tout. Il n’est donc pas étonnant que, comme nous le dit Proclus, la chôra soit, en fait, la déesse Rhéa. En hommage à la littérature révélatrice antique, comme les Oracles chaldaïques, Homère et Hésiode, Proclus fournit une élucidation non seulement philosophique, mais aussi théologique, de la chôra. À la différence de Platon, il théologise la Physique. (shrink)

Detlefsen (1986) reads Hilbert's program as a sophisticated defense of instrumentalism, but Feferman (1998) has it that Hilbert's program leaves significant ontological questions unanswered. One such question is of the reference of individual number terms. Hilbert's use of admittedly "meaningless" signs for numbers and formulae appears to impair his ability to establish the reference of mathematical terms and the content of mathematical propositions (Weyl (1949); Kitcher (1976)). The paper traces the history and context of Hilbert's reasoning about signs, which illuminates (...) Hilbert's account of mathematical objectivity, axiomatics, idealization, and consistency. (shrink)

Hermann von Helmholtz (1821-1894) participated in two of the most significant developments in physics and in the philosophy of science in the 19th century: the proof that Euclidean geometry does not describe the only possible visualizable and physical space, and the shift from physics based on actions between particles at a distance to the field theory. Helmholtz achieved a staggering number of scientific results, including the formulation of energy conservation, the vortex equations for fluid dynamics, the notion of free energy (...) in thermodynamics, and the invention of the ophthalmoscope. His constant interest in the epistemology of science guarantees his enduring significance for philosophy. (shrink)

Moti Mizrahi has argued that Thomas Kuhn does not have a good argument for the incommensurability of successive scientific paradigms. With Rouse, Andersen, and others, I defend a view on which Kuhn primarily was trying to explain scientific practice in Structure. Kuhn, like Hilary Putnam, incorporated sociological and psychological methods into his history of science. On Kuhn’s account, the education and initiation of scientists into a research tradition is a key element in scientific training and in his explanation of incommensurability (...) between research paradigms. The first part of this paper will explain and defend my reading of Kuhn. The second part will probe the extent to which Kuhn’s account can be supported, and the extent to which it rests on shaky premises. That investigation will center on Moti Mizrahi’s project, which aims to transform the Kuhnian account of science and of its history. While I do defend a modified kind of incommensurability, I agree that the strongest version of Kuhn’s account is steadfastly local and focused on the practice of science. (shrink)

This dissertation shows that Proclus provides a consistent reading of Plato's late dialogues, and develops a three level ontology which stands on its own. By augmenting the reserve of Platonist philosophy with Post Platonic developments of Greek mathematics and astronomy and physics, at points where Platonism ceased to provide operating principles, Proclus, reached for formulations which went beyond Plato. His own metaphysics, though sometimes obscured by theurgic allusions, grounds Being in an infinite One. ;One of the problems that Proclus attempts (...) to solve through the posit of three infinities, is that an iterative potential infinity, seen in the interval structure of the physical world, could divide to oblivion if uncolonized by Principle. The 'One Being', which brings Limit and noetic sameness, is itself entrapped in Self Reflexivity. An infinity of a third kind, one beyond all Limit and Unlimit is posed to solve this problem. This is Proclus' NeoPlatonic solution to the fact that Being alone, albeit under the rule of intellect, cannot guarantee itself. ;Platonism assumes a "universe" i.e. One grounding Many, which predetermines the place of all structure. $\rm A\nu\lambda o\gamma\iota\alpha$ is a principle of substitution which governs the visible cosmos and makes it comprehensible by mathematical formulations. Plato's emphasis on the self same as the epitome of Being, with circularity as the highest form for thought, helps Proclus provide a consistent account of: Creation ; Infinity as a Simultaneous Whole ; Soul and Nous, Dialectic is valorized over other forms of thought as most like $$ the eternal truth and a means to assimilation. Procession and reversion forms a circle which demonstrates a metaphysical successor of cosmic revolutions found to exist as the heavenly bodies carry out their noetic patterns. ;Finally Eternity encapsulates Time; but again its infinite circularity is only recouped by a One beyond all Limit which can carry out the Providence of a final cause. (shrink)

The idea that mythos and logos are incompatible, and that truth is a product of scientific and dialectical thinking, was certainly disproven by later Platonic philosophers. Deploying the works of Hesiod and Homer, Homeric Hymns and other such literature, they considered myth a valuable and significant augment to philosophical discourse. Plato’s denigration of myth gave his followers an incentive to read myth as allegory. The Stoics and first-century philosophers such as Philo, treated allegory as a legitimate interpretive strategy. The Middle (...) Platonists incorporated myth, for example, deifying the Monad and Dyad, as did 2nd century Platonists. Plutarch’s Isis and Osiris, for example, equates Isis and Osiris with form and matter: the god sows in matter logoi from himself. Porphyry’s allegorizing of Plato’s Cave of the Nymphs is another example. Plotinus is a strong influence on how the late Neoplatonists regarded myth. This paper argues that these philosophers’ use of allegory prepared the way for the Neoplatonists treatment of myth as inspired symbolism. Proclus and Syrianus, as reported by Hermias, did something more extreme by using mythology to construct inspired symbolic argument. Mythos becomes another type of logos, a vehicle for representing the invisible world of being, another kind of truth that can even serve a function in anagogic ascent. (shrink)

It is in the obscure terrain between the life-world of Greek science and technology and the language of its metaphysics that one sees the attempts of early navigators and map-makers to conceptualize what lies beyond the oikoumene. This interest later effects astronomy in terms of what is “beyond the heavens [ezo tes ouranos]” and then in metaphysics as a “Beyond Being [epekeina tes ousias],” an ideal Beyond proposed by Plato in Republic and one that is to eventually become a mainstay (...) of NeoPlatonism. Thus, the “fundamental act” that Romm describes in the above quote was not only taken up with geographical interest, but is one that can be seen as a preparatory gesture in a culture readying itself for the advent of metaphysics, a gesture that continued to make itself felt up until the last days of the Ancient Academy in the fifth century AD. The threads of the intellectual history of a Beyond Being find technological roots in the increasingly sophisticated acts of representation that one finds in early cartography, astronomy, and cosmology, one of which will be to mark boundaries around the heavens themselves and to call that Being. (shrink)

Soul is the self-moving, self-constituting entity linking the transcendent with the immanent. Proclus distinguishes many types of souls. This chapter concentrates on the World Soul and the rational human soul. The World Soul infuses the sensible, temporal, divided, and material cosmos with unity and Forms ultimately deriving from the One and Intelligible Being, in a manner reminiscent of human phantasia. The mathematical psychology of the Timaeus is explained as referring to the Soul’s activity, rather than its essence. Concerning the human (...) soul, with its eternal essence and temporal activity, the authors concentrate on the function and nature of the many ‘vehicles’, assisting the soul’s descent and, in a different manner, its ascent. (shrink)